Carignan S, Staples C A, Müller N L
Department of Radiology, University of British Columbia, Vancouver, Canada.
Radiology. 1995 Oct;197(1):53-8. doi: 10.1148/radiology.197.1.7568853.
To assess the computed tomographic (CT) findings of intrathoracic lymphoproliferative disorders in the immunocompromised patient.
The authors retrospectively reviewed CT scans of the chest in 18 consecutive patients with pathologically proved intrathoracic lymphoproliferative disorders. Twelve patients had the acquired immunodeficiency syndrome (AIDS), and six were receiving immunosuppressive therapy. Final diagnosis included AIDS-related diffuse lymphoid hyperplasia (n = 1), lymphocytic interstitial pneumonia (LIP) (n = 3), posttransplantation lymphoproliferative disorders (PTLDs) (n = 4), and lymphoma (n = 10).
Diffuse areas of ground-glass attenuation were found in the patient with lymphoid hyperplasia and the three patients with LIP. The four patients with PTLDs had multiple, well-circumscribed pulmonary nodules, and nodules in three of the four patients had a halo of ground-glass attenuation. Nine of the 10 patients with lymphoma had well-circumscribed nodules or nodules with consolidation. Mediastinal lymph node enlargement was present in two patients with PTLDs and three patients with lymphoma.
The intrathoracic CT findings of lymphoproliferative disorders appear to be similar in immunocompromised patients with and without AIDS and are usually extranodal.
评估免疫功能低下患者胸内淋巴增殖性疾病的计算机断层扫描（CT）表现。
作者回顾性分析了18例经病理证实患有胸内淋巴增殖性疾病患者的胸部CT扫描结果。其中12例患有获得性免疫缺陷综合征（AIDS），6例正在接受免疫抑制治疗。最终诊断包括AIDS相关弥漫性淋巴组织增生（n = 1）、淋巴细胞间质性肺炎（LIP）（n = 3）、移植后淋巴增殖性疾病（PTLDs）（n = 4）和淋巴瘤（n = 10）。
淋巴组织增生患者及3例LIP患者出现磨玻璃样密度影的弥漫区域。4例PTLDs患者有多个边界清晰的肺结节，4例中的3例结节周围有磨玻璃样密度影晕环。10例淋巴瘤患者中有9例有边界清晰的结节或实变结节。2例PTLDs患者和3例淋巴瘤患者出现纵隔淋巴结肿大。
免疫功能低下患者无论是否患有AIDS，其胸内淋巴增殖性疾病的CT表现似乎相似，且通常为结外病变。
