Takeda Sho, Nakanishi Toshio, Nakazawa Makoto
Division of Pediatric Cardiology, The Heart Institute of Japan, Tokyo Women's Medical University, Tokyo, Japan.
Pediatr Int. 2005 Aug;47(4):392-6. doi: 10.1111/j.1442-200x.2005.02076.x.
Infective endocarditis (IE) is still one of the major complications of congenital heart disease and, therefore, prevention has always been an important issue. But there has been no large scale investigation of IE in Japan.
Clinical and microbiological features in 183 patients with congenital heart diseases complicated with infective endocarditis (IE), which were treated in our institute in the last 28 years, were reviewed.
During the period, the age distribution of the patients shifted to an older age; 80% were older than 15 years in the latest 7 year period. In the underlying diseases more complex conditions increased, such as the post Rastelli operation. Dental or oral diseases were the major preceding events and Streptococcus was the major pathogen throughout the study periods in the data.
The result indicates the importance of continuing education for the prevention of IE and oral hygiene especially in adult patients with a risk for IE.
感染性心内膜炎（IE）仍是先天性心脏病的主要并发症之一，因此，预防一直是一个重要问题。但日本尚未对IE进行大规模调查。
回顾了我院过去28年收治的183例先天性心脏病合并感染性心内膜炎（IE）患者的临床和微生物学特征。
在此期间，患者的年龄分布向老年转移；在最近7年中，80%的患者年龄超过15岁。在基础疾病方面，更复杂的情况有所增加，如Rastelli手术后。牙科或口腔疾病是主要的前驱事件，在整个研究期间，链球菌是数据中的主要病原体。
结果表明，尤其是对于有IE风险的成年患者，持续开展预防IE的教育和口腔卫生教育非常重要。
