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[缺血性心脏病患者冠状动脉血流变化、心肌能量代谢与高胰岛素血症之间的关系]

[Relationships between changes of coronary blood flow, energy metabolism of the myocardium, and hyperinsulinemia in patients with ischemic heart disease].

作者信息

Telkova I L, Tepliakov A T

出版信息

Kardiologiia. 2005;45(8):61-8.

PMID:16091647
Abstract

The paper reviews current data on relationships between coronary blood flow, hemodynamics, and myocardial energy metabolism during phenomena of stunned and hibernating myocardium in patients with ischemic heart disease. These data has been obtained with various modern techniques including positron emission tomography with (18)F-flourodeoxyglucose, (11)C-palmitate and (11)C-acetate. Possible association of remodeling of cardiac energetic metabolism under conditions of chronic ischemia and hyperinsulinemia in patients at various stages of ischemic heart disease is interpreted as compensatory reaction to elevation of myocardial glucose requirements.

摘要

本文综述了关于缺血性心脏病患者心肌顿抑和冬眠心肌现象期间冠状动脉血流、血流动力学和心肌能量代谢之间关系的现有数据。这些数据是通过各种现代技术获得的,包括使用(18)F-氟脱氧葡萄糖、(11)C-棕榈酸酯和(11)C-乙酸盐的正电子发射断层扫描。缺血性心脏病不同阶段患者在慢性缺血和高胰岛素血症条件下心脏能量代谢重塑的可能关联被解释为对心肌葡萄糖需求增加的代偿反应。

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[Relationships between changes of coronary blood flow, energy metabolism of the myocardium, and hyperinsulinemia in patients with ischemic heart disease].[缺血性心脏病患者冠状动脉血流变化、心肌能量代谢与高胰岛素血症之间的关系]
Kardiologiia. 2005;45(8):61-8.
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Insulin-induced increment of coronary flow reserve is not abolished by dexamethasone in healthy young men.在健康年轻男性中,胰岛素诱导的冠状动脉血流储备增加不会被地塞米松消除。
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Myocardial Ischemia: Lack of Coronary Blood Flow or Myocardial Oxygen Supply/Demand Imbalance?心肌缺血:是冠状动脉血流不足还是心肌供需失衡?
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Regional wall motion abnormalities in stunned and hibernating myocardium.顿抑心肌和冬眠心肌的节段性室壁运动异常。
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Cardiac metabolism in myocardial ischemia.心肌缺血中的心脏代谢
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