Telkova I L, Tepliakov A T
Kardiologiia. 2005;45(8):61-8.
The paper reviews current data on relationships between coronary blood flow, hemodynamics, and myocardial energy metabolism during phenomena of stunned and hibernating myocardium in patients with ischemic heart disease. These data has been obtained with various modern techniques including positron emission tomography with (18)F-flourodeoxyglucose, (11)C-palmitate and (11)C-acetate. Possible association of remodeling of cardiac energetic metabolism under conditions of chronic ischemia and hyperinsulinemia in patients at various stages of ischemic heart disease is interpreted as compensatory reaction to elevation of myocardial glucose requirements.
本文综述了关于缺血性心脏病患者心肌顿抑和冬眠心肌现象期间冠状动脉血流、血流动力学和心肌能量代谢之间关系的现有数据。这些数据是通过各种现代技术获得的,包括使用(18)F-氟脱氧葡萄糖、(11)C-棕榈酸酯和(11)C-乙酸盐的正电子发射断层扫描。缺血性心脏病不同阶段患者在慢性缺血和高胰岛素血症条件下心脏能量代谢重塑的可能关联被解释为对心肌葡萄糖需求增加的代偿反应。