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[通过口腔pH测试对抗菌剂疗效的比较研究]

[Comparative study by pH-tests of the efficacy of antimicrobial agents in oral cavity].

作者信息

Rumiantsev V A, Iusufov M V, Khiutti N V, Moskaleva I V, Slobodina E V

出版信息

Stomatologiia (Mosk). 2005;84(4):4-7.

PMID:16091697
Abstract

The opportunity of use stimulated by sucrose solutions and urea test pH changes of the mixed saliva were investigated with the purpose of an estimation of efficiency of antiseptic and hygienic means action. Research is carried out on 37 students who have been specially picked up in 3 groups: "A" -- with low activity of caries without periodontitis, "B" -- caries-susceptible and "C" -- with gingivitis and periodontitis. It appeared possible with the help of pH-measuring of saliva to compare antiseptic action in an oral cavity of 4 popular antiseptics: the combined gel with chlorhexidine and metronidazole, and also anticarious toothpaste in the form of application and in combination with cleaning teeth by a brush. The offered tests allow to reveal primary action of antiseptic means for the microflora causing either caries or inflammatory periodontal disease.

摘要

为评估防腐和卫生手段的作用效果,研究了蔗糖溶液和尿素刺激下混合唾液pH值变化的利用机会。对37名学生进行了研究,他们被特意分为3组:“A”组——龋齿活动度低且无牙周炎;“B”组——易患龋齿;“C”组——患有牙龈炎和牙周炎。借助唾液pH值测量,比较4种常用防腐剂在口腔中的防腐作用成为可能:含氯己定和甲硝唑的复方凝胶,以及涂抹型防龋牙膏和与牙刷刷牙相结合使用的防龋牙膏。所提供的测试能够揭示防腐手段对导致龋齿或炎症性牙周疾病的微生物群的主要作用。

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