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关节内注射透明质酸钠对肩周炎患者而言是一种替代治疗方法吗?

Is intraarticular sodium hyaluronate injection an alternative treatment in patients with adhesive capsulitis?

作者信息

Calis Mustafa, Demir Huseyin, Ulker Sener, Kirnap Mehmet, Duygulu Fuat, Calis Havva Talay

机构信息

Department of Physical Medicine and Rehabilitation, Erciyes University Medical Faculty, Kayseri, Turkey.

出版信息

Rheumatol Int. 2006 Apr;26(6):536-40. doi: 10.1007/s00296-005-0022-2. Epub 2005 Aug 10.

Abstract

The aim of this study was to compare the efficacy of sodium hyaluronate (SH) injection with the most common treatment methods, intraarticular steroid injection and physical therapy modalities in patients with adhesive capsulitis (AC). A total of 95 shoulders of 90 patients were included in the study and were randomized in four groups. The patients were treated with SH injection (group 1), triamsinolone acetonide (group 2) or physical therapy modalities (group 3). Group 4 patients were served as controls. Pain severity, passive ranges of motion and functional considerations were measured before, and 15 days and 3 months after the treatments. In all treatment groups, there were significant improvements at both the 15th day and third month in all parameters (for each, p<0.001). The passive abduction values on the 15th day was found significantly higher in group 3 when compared with group 1 and controls (for each, p<0.001). At the third month, the passive abduction values of the groups 2 and 3 were improved when compared with the control group (p<0.001). Constant score was higher in group 3 on 15th day when compared with group 1. At the third month, all treatment groups were improved significantly compared with control group (p<0.001). We provided the best results in physical therapy modalities applied group for AC treatment. However, we think that SH injection may be administered as an alternative treatment method.

摘要

本研究的目的是比较透明质酸钠(SH)注射与最常用治疗方法(关节内注射类固醇和物理治疗方式)在粘连性关节囊炎(AC)患者中的疗效。本研究共纳入90例患者的95个肩部,并随机分为四组。患者分别接受SH注射治疗(第1组)、曲安奈德治疗(第2组)或物理治疗方式(第3组)。第4组患者作为对照组。在治疗前、治疗后15天和3个月测量疼痛严重程度、被动活动范围和功能指标。在所有治疗组中,所有参数在第15天和第3个月均有显著改善(每项,p<0.001)。第3组在第1天的被动外展值与第1组和对照组相比显著更高(每项,p<0.001)。在第3个月时,第2组和第3组的被动外展值与对照组相比有所改善(p<0.001)。第3组在第15天的Constant评分高于第1组。在第3个月时,所有治疗组与对照组相比均有显著改善(p<0.001)。我们发现物理治疗方式应用组在AC治疗中取得了最佳效果。然而,我们认为SH注射可作为一种替代治疗方法。

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