Quinn Niall P
Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, London, UK.
Mov Disord. 2005 Aug;20 Suppl 12:S5-S10. doi: 10.1002/mds.20534.
The diagnosis of multiple system atrophy (MSA) in life remains entirely clinical. Consensus diagnostic criteria have been developed, but their use does not particularly render a diagnosis of MSA more accurate than are clinicians' diagnoses. Some patients may not fulfill the stipulated core diagnostic criteria, yet display many so-called red flags pointing toward MSA. The additional usefulness of these red flags and of a variety of investigations currently is being investigated, with a view to some of them being incorporated in future sets of diagnostic criteria.
多系统萎缩(MSA)的生前诊断完全依赖临床。目前已制定了共识诊断标准,但这些标准的应用并没有使MSA的诊断比临床医生的诊断更准确。一些患者可能不符合规定的核心诊断标准,但却表现出许多指向MSA的所谓警示信号。目前正在研究这些警示信号以及各种检查的额外作用,以期将其中一些纳入未来的诊断标准中。