Minocycline-induced black thyroid gland: Medical curiosity or a marker for papillary cancer?
作者信息
Birkedal C, Tapscott W J, Giadrosich K, Spence R K, Sperling D
机构信息
Department of Surgery, Baptist Health Systems, Birmingham, Alabama, USA.
出版信息
Curr Surg. 2001 Sep-Oct;58(5):470-1. doi: 10.1016/s0149-7944(01)00476-7.
Abstract
PURPOSE
Black pigmentation of the thyroid gland is a rare side effect of minocycline.
METHODS
Only 26 cases, in addition to the 2 we present, have been reported in the literature. Eleven cases of thyroid carcinoma associated with black thyroid syndrome have been reported.
CONCLUSIONS
The incidence of papillary cancer may be increased in thyroid glands stained by the minocycline pigment, which warrants an increased index of suspicion in patients who develop thyroid nodules and have previously been treated with minocycline.
摘要
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