Edwards Erik, Soltani Maryam, Deouell Leon Y, Berger Mitchel S, Knight Robert T
Department of Psychology, University of California, Berkeley, 94720, USA.
J Neurophysiol. 2005 Dec;94(6):4269-80. doi: 10.1152/jn.00324.2005. Epub 2005 Aug 10.
We recorded electrophysiological responses from the left frontal and temporal cortex of awake neurosurgical patients to both repetitive background and rare deviant auditory stimuli. Prominent sensory event-related potentials (ERPs) were recorded from auditory association cortex of the temporal lobe and adjacent regions surrounding the posterior Sylvian fissure. Deviant stimuli generated an additional longer latency mismatch response, maximal at more anterior temporal lobe sites. We found low gamma (30-60 Hz) in auditory association cortex, and we also show the existence of high-frequency oscillations above the traditional gamma range (high gamma, 60-250 Hz). Sensory and mismatch potentials were not reliably observed at frontal recording sites. We suggest that the high gamma oscillations are sensory-induced neocortical ripples, similar in physiological origin to the well-studied ripples of the hippocampus.
我们记录了清醒神经外科患者左额叶和颞叶皮质对重复性背景听觉刺激和罕见偏差听觉刺激的电生理反应。在颞叶听觉联合皮质以及西尔维安裂后部周围的相邻区域记录到了显著的感觉事件相关电位（ERP）。偏差刺激产生了额外的潜伏期更长的失配反应，在颞叶更靠前的部位最为明显。我们在听觉联合皮质中发现了低伽马（30 - 60赫兹）活动，并且还显示出存在高于传统伽马范围的高频振荡（高伽马，60 - 250赫兹）。在额叶记录部位未可靠观察到感觉和失配电位。我们认为，高伽马振荡是感觉诱导的新皮质涟漪，其生理起源与已得到充分研究的海马体涟漪相似。
