乳糜泻的内镜检查
Endoscopy in celiac disease.
作者信息
Lee Susie K, Green Peter H R
机构信息
Celiac Disease Center, Columbia University College of Physicians, New York, New York, USA.
出版信息
Curr Opin Gastroenterol. 2005 Sep;21(5):589-94. doi: 10.1097/01.mog.0000174218.00333.19.
PURPOSE OF REVIEW
The primary objective of this review is to highlight the evidence for the role of endoscopy in celiac disease.
RECENT FINDINGS
Evidence is presented that the endoscopic markers of celiac disease are specific although not sensitive for the disease. Villous atrophy, the hallmark of celiac disease, is patchy in the duodenum, and various techniques may identify areas of villous atrophy. These methods include magnification endoscopy and chromoendoscopy. The most recent innovation, video capsule endoscopy, may be of value in the diagnosis of celiac disease and in the assessment of patients with complicated celiac disease.
SUMMARY
Endoscopy and duodenal biopsies are the mainstay for diagnosing celiac disease. Although characteristic endoscopic features may be useful, their absence does not exclude celiac disease. Random biopsy, even of normal-appearing mucosa is necessary for the diagnosis of celiac disease.
综述目的
本综述的主要目的是强调内镜检查在乳糜泻中的作用证据。
最新发现
有证据表明，乳糜泻的内镜标志物具有特异性，尽管对该疾病并不敏感。绒毛萎缩是乳糜泻的标志，在十二指肠中呈斑片状，各种技术可能有助于识别绒毛萎缩区域。这些方法包括放大内镜检查和色素内镜检查。最新的创新技术——视频胶囊内镜检查，可能在乳糜泻的诊断以及复杂乳糜泻患者的评估中具有价值。
总结
内镜检查和十二指肠活检是诊断乳糜泻的主要手段。虽然典型的内镜特征可能有用，但缺乏这些特征并不能排除乳糜泻。对于乳糜泻的诊断，即使是外观正常的黏膜进行随机活检也是必要的。
Zotero 插件