Buzbee T M, Legha S S
Department of Medical Oncology, M.D. Anderson Cancer Center, Houston, Texas 77030.
Tumori. 1992 Feb 29;78(1):47-8. doi: 10.1177/030089169207800111.
We report a case of spontaneous splenic rupture in a patient with metastatic melanoma. Spontaneous splenic rupture without previous trauma has been observed in various pathological conditions such as infectious mononucleosis, malaria, typhoid fever and, rarely, neoplasms affecting the spleen. There have been several reported cases of splenic rupture in leukemias. Despite the high incidence of splenic metastases in metastatic melanoma, there have been only 3 cases of spontaneous splenic rupture reported in the past.
我们报告一例转移性黑色素瘤患者发生自发性脾破裂的病例。在各种病理状况下,如传染性单核细胞增多症、疟疾、伤寒热,以及罕见的影响脾脏的肿瘤,均观察到无既往创伤史的自发性脾破裂。白血病患者中已有多例脾破裂的报告。尽管转移性黑色素瘤中脾转移的发生率很高,但过去仅报告过3例自发性脾破裂病例。