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[1991年至2001年波兰喉癌和下咽癌的流行病学演变及临床特征]

[The evolution of epidemiology and clinical characteristics of laryngeal and hypopharyngeal carcinoma in Poland from 1991 to 2001].

作者信息

Bień Stanisław, Kamiński Bartłomiej, Zyłka Stanisław, Mezyk Ryszard, Piasta Zdzisław, Markowski Jarosław, Paluch Jarosław, Kordylewska Magdalena, Wierzbicka Małgorzata, Morshed Kamal, Gryczyński Maciej, Murlewska Anna, Modrzejewski Maciej, Składzień Jacek, Jaworowska Ewa, Matyja Grzegorz, Burduk Paweł, Müller Maciej, Kowalska Bozena, Mikaszewski Bogusław, Misiołek Maciej, Namysłowski Grzegorz, Bruzgielewicz Antoni, Osuch-Wójcikiewicz Ewa, Szymański Leszek, Krecicki Tomasz, Karasiewicz Piotr, Mikulewicz Wojciech, Pietrysiak Aldona, Jurkiewicz Dariusz, Kubik Paweł, Janeczek Tadeusz

机构信息

Dział Chirurgii Głowy i Szyi Swietokrzyskiego Centrum Onkologii w Kielcach.

出版信息

Otolaryngol Pol. 2005;59(2):169-81.

Abstract

On the base of retrospective analysis of 12,888 cases of carcinoma of larynx and hypopharynx, diagnosed in 19 ENT Departments in Poland from 1991 to 2001, the assessment of basic epidemiological data, including the localization of tumor and stage of local and clinical advancement of the disease at the time of diagnosis has been conducted. In analyzed period of 11 years the trends to change of the mentioned above parameters has been examined. The significant increase of female patients in this period was observed, with average proportion M:F = 8:1. The glottis localization of carcinoma dominated (47.6%), followed by supraglottis (40.8%) and pyriform fossa (7.8%), with significant increase of pyriform fossa tumors in the analyzed period of 11 years. In the majority of cases the carcinoma of larynx and hypopharynx was diagnosed in the advanced stage (T3 + T4) of local disease, with the highest percentage in localization within the pyriform fossa (81.0%), and the lowest percentage in glottis tumors (45.6%). The regional lymph nodes metastases has been diagnosed in 46.7% of the analyzed group, with the highest percentage in tumors localized in pyriform fossa (82.9%), and the lowest percentage in tumors of glottis localization (33.1%). In the 11 years time the significant drop down of N0 cases and tendency to increase of N2 and N3 in the supraglottis localization of tumor. The distant metastases in the analyzed group at the time of diagnosis has been registered in 2.0%, with the highest percentage in posterior pharyngeal wall (7.6%) and pyriform fossa (7.4%). The authors postulate the renewal of prospective study on epidemiology, clinical characteristics and treatment results of larynx and hypopharynx carcinoma in Poland.

摘要

在对1991年至2001年波兰19个耳鼻喉科诊断的12888例喉癌和下咽癌病例进行回顾性分析的基础上,对基本流行病学数据进行了评估,包括肿瘤的定位以及诊断时疾病的局部和临床进展阶段。在11年的分析期内,研究了上述参数的变化趋势。观察到这一时期女性患者显著增加,平均男女比例为8:1。喉癌以声门区定位为主(47.6%),其次是声门上区(40.8%)和梨状窝(7.8%),在11年的分析期内梨状窝肿瘤显著增加。在大多数病例中,喉癌和下咽癌在局部疾病晚期(T3 + T4)被诊断出来,梨状窝定位的比例最高(81.0%),声门区肿瘤的比例最低(45.6%)。46.7%的分析组患者被诊断有区域淋巴结转移,梨状窝定位的肿瘤转移比例最高(82.9%),声门区肿瘤转移比例最低(33.1%)。在11年时间里,声门上区肿瘤定位的N0病例显著下降,N2和N3有增加趋势。分析组在诊断时远处转移的发生率为2.0%,咽后壁(7.6%)和梨状窝(7.4%)的比例最高。作者建议在波兰重新开展关于喉癌和下咽癌流行病学、临床特征及治疗结果的前瞻性研究。

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