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木糖氧化产碱杆菌——慢性耳部感染的病原体

[Alcaligenes xylosoxidans--a pathogen of chronic ear infection].

作者信息

Wiatr Maciej, Morawska Agnieszka, Składzień Jacek, Kedzierska Jolanta

机构信息

Klinika Otolaryngologii Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowie.

出版信息

Otolaryngol Pol. 2005;59(2):277-80.

Abstract

INTRODUCTION

We discuss a case of a 48-year old man admitted to our Department with symptoms of chronic ear infection, that didn't answer to typical conservative treatment. The culture of the discharge was positive for Alcaligenes xylosoxidans.

MATERIAL AND METHODS

We report characteristic features of that bacteria and we compare them with features of other pathogens typical for otitis media. We present performed treatment too.

RESULTS

Alcaligenes xylosoxidans is a nonfermenting gram-negative rod. It can be confused with other nonfermentive, gram-negative rods, especially Pseudomonas species, in clinical specimens so that its role as a significant pathogen may be underestimated. Alcaligenes xylosoxidans is a part of normal human flora, especially skin and gastrointestinal tract, and can cause serious infections in human (especially in patients with immunodeficiency and premature children).

CONCLUSIONS

Reports about Alcaligenes xylosoxidans as a cause of chronic otitis media are very rare and it can be supposed to stay a new kind of ear infection.

摘要

引言

我们讨论一例48岁男性患者,因慢性耳部感染症状入院,对典型的保守治疗无反应。分泌物培养结果显示木糖氧化产碱杆菌呈阳性。

材料与方法

我们报告了该细菌的特征,并将其与中耳炎其他典型病原体的特征进行比较。我们还介绍了所采取的治疗方法。

结果

木糖氧化产碱杆菌是一种非发酵革兰氏阴性杆菌。在临床标本中,它可能会与其他非发酵革兰氏阴性杆菌,尤其是假单胞菌属混淆,因此其作为重要病原体的作用可能被低估。木糖氧化产碱杆菌是人类正常菌群的一部分,尤其是皮肤和胃肠道中的菌群,可导致人类严重感染(尤其是免疫缺陷患者和早产儿)。

结论

关于木糖氧化产碱杆菌作为慢性中耳炎病因的报道非常罕见,可以认为它是一种新型耳部感染。

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