Endo Shunsuke, Saito Noriko, Hasegawa Tsuyoshi, Sato Yukio, Sohara Yasunori
Division of General Thoracic Surgery, Department of Surgery, Jichi Medical School, Minamikawachi, Kawachi-gun, Tochigi 329-0498, Japan.
Jpn J Thorac Cardiovasc Surg. 2005 Jul;53(7):369-71. doi: 10.1007/s11748-005-0052-4.
A 71-year-old man who had undergone surgery for stage II adenocarcinoma of the lung followed by adjuvant tegafur-uracil (UFT; 300 mg/day) therapy was admitted. Multiple nodules were found in both lungs on chest radiographs obtained 1.5 years after the surgery. Imaging characteristics of the nodules resembled those of pulmonary metastases. Histologic assessment of a biopsy specimen obtained during thoracoscopic resection revealed pulmonary cryptococcosis. The patient was administered 200 mg/day fluconazole for 6 months. Physicians need to be aware of the possibility of pulmonary cryptococcosis mimicking pulmonary metastases in patients treated with UFT after surgery for lung cancer.
一名71岁男性因II期肺腺癌接受手术治疗，术后接受替加氟-尿嘧啶（UFT；300毫克/天）辅助治疗，随后入院。术后1.5年进行的胸部X线检查发现双肺有多个结节。这些结节的影像学特征类似于肺转移瘤。经胸腔镜切除获取的活检标本的组织学评估显示为肺隐球菌病。该患者接受了为期6个月、每日200毫克氟康唑的治疗。医生需要意识到，在肺癌手术后接受UFT治疗的患者中，肺隐球菌病可能会酷似肺转移瘤。
