Darmoul M, Bouhaouala M H, Rezgui M
Unite de Neurochirurgie, Hôpital des FSI, La Marsa Tunisie.
Presse Med. 2005 Jul 2;34(12):859-60. doi: 10.1016/s0755-4982(05)84064-3.
Intradiscal injection of triamcinolone hexacetonide, used to treat sciatica caused by herniated discs was discontinued after discovery that it was followed in some cases by epidural calcification.
Ten years after an intradiscal injection at L4-L5, a 40 year-old man developed voluminous perivertebral, bilateral foraminal and intraductal calcifications that compressed the dural sheath. After preliminary excision, these calcifications recurred and required further excision, followed by posterior lateral grafting and osteosynthesis.
Calcifications following intradiscal injections are symptomatic in 14 to 68% of cases. They require radical surgical treatment to avoid recurrence.
在发现椎间盘内注射己曲安奈德治疗椎间盘突出引起的坐骨神经痛在某些情况下会继发硬膜外钙化后,该治疗方法已停止使用。
一名40岁男性在L4-L5椎间盘内注射十年后,出现大量椎旁、双侧椎间孔及椎管内钙化,压迫硬膜囊。初步切除后,钙化复发,需要进一步切除,随后进行后外侧植骨和骨固定术。
椎间盘内注射后发生钙化的病例中,14%至68%有症状。需要进行根治性手术治疗以避免复发。