Visser Jasper E, Bloem Bastiaan R
Department of Neurology, University Medical Center St Radboud, Nijmegen, The Netherlands.
Neural Plast. 2005;12(2-3):161-74; discussion 263-72. doi: 10.1155/NP.2005.161.
In this review paper, we summarize the important contributions of the basal ganglia to the regulation of postural control. After a brief overview of basal ganglia circuitries, the emphasis is on clinical observations in patients with focal lesions in parts of the basal ganglia, as the impairments seen here can serve to highlight the normal functions of the basal ganglia nuclei in postural control. Two particularly relevant functions are discussed in detail: first, the contribution of the basal ganglia to flexibility and to gaining control of balance-correcting responses, including the ability to lend priority to the elements of a postural task; and second, processing afferent information by the basal ganglia, which is increasingly recognized as being highly relevant for postural control.
在这篇综述论文中,我们总结了基底神经节对姿势控制调节的重要贡献。在简要概述基底神经节的神经回路后,重点关注基底神经节部分区域局灶性病变患者的临床观察结果,因为在此观察到的功能障碍有助于突出基底神经节核在姿势控制中的正常功能。详细讨论了两个特别相关的功能:第一,基底神经节对灵活性以及获得平衡纠正反应控制的贡献,包括对姿势任务要素赋予优先级的能力;第二,基底神经节对传入信息的处理,这一点越来越被认为与姿势控制高度相关。