急性冠脉综合征出院时贫血与生存的关系。
Relation of anemia at discharge to survival after acute coronary syndromes.
作者信息
Vaglio Joseph, Safley David M, Rahman Mohamed, Kosiborod Mikhail, Jones Philip, Thompson Randall, Krumholz Harlan M, Spertus John A
机构信息
Mid America Heart Institute of Saint Luke's Hospital, Missouri, USA.
出版信息
Am J Cardiol. 2005 Aug 15;96(4):496-9. doi: 10.1016/j.amjcard.2005.04.008.
Two-year survival rate was assessed among 1,038 patients who had acute coronary syndromes that were classified by discharge hematocrit values as normal (>39%, n = 360, 34.7%), mildly anemic (33.1% to 39%, n = 430, 41.4%), or moderately/severely anemic (< or = 33%, n = 248, 23.9%). Worsening anemia was associated with a decreased 2-year survival rate (normal 95.8%, mild anemia 91.2%, moderate/severe anemia 81.5%, p < 0.001). In multivariable analyses, adjusted hazard ratios for all-cause mortality were 1.57 (95% confidence interval 0.82 to 2.96) for mild anemia and 2.46 (95% confidence interval 1.25 to 4.85) for moderate/severe anemia.
对1038例急性冠脉综合征患者的两年生存率进行了评估，这些患者根据出院时的血细胞比容值分为正常（>39%，n = 360，34.7%）、轻度贫血（33.1%至39%，n = 430，41.4%）或中度/重度贫血（≤33%，n = 248，23.9%）。贫血加重与两年生存率降低相关（正常为95.8%，轻度贫血为91.2%，中度/重度贫血为81.5%，p < 0.001）。在多变量分析中，轻度贫血的全因死亡率调整风险比为1.57（95%置信区间0.82至2.96），中度/重度贫血为2.46（95%置信区间1.25至4.85）。
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