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外淋巴瘘的手术治疗:波特兰经验

Surgical management of perilymphatic fistulas: a Portland experience.

作者信息

Black F O, Pesznecker S, Norton T, Fowler L, Lilly D J, Shupert C, Hemenway W G, Peterka R J, Jacobson E S

机构信息

Department of Neurotology, Good Samaritan Hospital and Medical Center, Portland, Oregon 97210.

出版信息

Am J Otol. 1992 May;13(3):254-62.

PMID:1609855
Abstract

A comprehensive review of our series of surgical perilymphatic fistula (PLF) repairs, as well as a review of published results from other otologists, suggested an unacceptably high rate of postoperative PLF recurrence. Some recurrences were related to specific events (i.e., coughing, strenuous activity, Valsalva-type maneuvers). However many cases had no apparent cause. Rather, the patients' symptoms recurred spontaneously, and at reoperation the graft was seen to have not "taken," suggesting graft failure rather than "patient failure." After a critical evaluation of current PLF surgical procedures and state-of-the-art concepts of wound healing, we developed a new surgical technique for PLF closure. Combining the use of laser graft-site preparation, an autologous fibrin glue "buttress," and a program of postoperative activity restriction, the new procedure allowed us to achieve statistically significant improvements in graft retention and surgical outcome, with recurrences dropping from 27 percent to 8 percent. In addition, complete resolution or significant symptomatic improvement occurred in 89 percent of patients with vertigo and/or dizziness and in 84 percent with disequilibrium. We conclude that this new surgical technique is an important addition to the otologic surgeon's arsenal for PLF management.

摘要

对我们一系列手术治疗外淋巴瘘(PLF)的回顾,以及对其他耳科医生公布结果的回顾表明,术后PLF复发率高得令人难以接受。一些复发与特定事件有关(如咳嗽、剧烈活动、瓦尔萨尔瓦动作)。然而,许多病例没有明显原因。相反,患者症状自发复发,再次手术时发现移植物未“成活”,提示是移植物失败而非“患者失败”。在对当前PLF手术程序和伤口愈合的最新概念进行批判性评估后,我们开发了一种新的PLF闭合手术技术。结合使用激光移植物部位制备、自体纤维蛋白胶“支撑”和术后活动限制方案,新手术使我们在移植物保留和手术结果方面取得了统计学上的显著改善,复发率从27%降至8%。此外,89%有眩晕和/或头晕的患者以及84%有平衡失调的患者症状完全缓解或有显著改善。我们得出结论,这种新手术技术是耳科医生治疗PLF的重要补充手段。

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