神经性厌食症中食欲与胆囊收缩素分泌的调节
Regulation of appetite and cholecystokinin secretion in anorexia nervosa.
作者信息
Geracioti T D, Liddle R A, Altemus M, Demitrack M A, Gold P W
机构信息
Clinical Neuroendocrinology Branch, NIMH, Bethesda, Md.
出版信息
Am J Psychiatry. 1992 Jul;149(7):958-61. doi: 10.1176/ajp.149.7.958.
PMID:1609878
Abstract
Six patients with anorexia nervosa, the same patients after weight normalization, and six healthy control subjects had similar fasting and postprandial plasma cholecystokinin concentrations. These data do not support the hypothesis that low levels of hunger and food intake in anorexic patients reflect hypersecretion of this endogenous hormone, which is thought to inhibit hunger, promote satiety, and reduce feeding.
摘要
6名神经性厌食症患者、体重恢复正常后的同一批患者以及6名健康对照者的空腹和餐后血浆胆囊收缩素浓度相似。这些数据并不支持以下假说：厌食症患者饥饿感和食物摄入量较低反映了这种内源性激素的分泌过多，而这种激素被认为可抑制饥饿感、促进饱腹感并减少进食。
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