刚地弓形虫三种主要毒株之间的差异及其与受感染宿主的特定相互作用。

Differences among the three major strains of Toxoplasma gondii and their specific interactions with the infected host.

作者信息

Saeij Jeroen P J, Boyle Jon P, Boothroyd John C

机构信息

Stanford University School of Medicine, Department of Microbiology and Immunology, Fairchild Building D305, 300 Pasteur Drive, Stanford, CA 94305-5124, USA.

出版信息

Trends Parasitol. 2005 Oct;21(10):476-81. doi: 10.1016/j.pt.2005.08.001.

DOI:10.1016/j.pt.2005.08.001

PMID:16098810

Abstract

Toxoplasma gondii is one of the most successful protozoan parasites owing to its ability to manipulate the immune system and establish a chronic infection. There are many T. gondii strains but the majority identified in Europe and North America falls into three distinct clonal lineages. Many studies have investigated the ability of T. gondii to manipulate its host but few have examined directly whether the three lineages differ in this ability.

摘要

刚地弓形虫是最成功的原生动物寄生虫之一，这得益于其操纵免疫系统并建立慢性感染的能力。刚地弓形虫有许多菌株，但在欧洲和北美鉴定出的大多数菌株可分为三个不同的克隆谱系。许多研究调查了刚地弓形虫操纵其宿主的能力，但很少有研究直接考察这三个谱系在这种能力上是否存在差异。