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涂覆纳米颗粒的外科口罩的抗菌效果

Antimicrobial effect of surgical masks coated with nanoparticles.

作者信息

Li Y, Leung P, Yao L, Song Q W, Newton E

机构信息

Institute of Textiles and Clothing, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China.

出版信息

J Hosp Infect. 2006 Jan;62(1):58-63. doi: 10.1016/j.jhin.2005.04.015. Epub 2005 Aug 15.

Abstract

This study assessed the antimicrobial activity of nanoparticles (consisting of a mixture of silver nitrate and titanium dioxide) and nanoparticle-coated facemasks to protect against infectious agents. The minimum inhibitory concentrations of the nanoparticles against Escherichia coli and Staphylococcus aureus were 1/128 and 1/512, respectively. The antibacterial activity of nanoparticle-coated masks was quantified according to the procedures of AATCC 100-1999. A 100% reduction in viable E. coli and S. aureus was observed in the coated mask materials after 48 h of incubation. Skin irritation was not observed in any of the volunteers who wore the facemasks. Nanoparticles show promise when applied as a coating to the surface of protective clothing in reducing the risk of transmission of infectious agents.

摘要

本研究评估了纳米颗粒(由硝酸银和二氧化钛的混合物组成)及纳米颗粒涂层口罩对预防感染因子的抗菌活性。纳米颗粒对大肠杆菌和金黄色葡萄球菌的最低抑菌浓度分别为1/128和1/512。根据美国纺织化学家和染色家协会(AATCC)100 - 1999标准程序对纳米颗粒涂层口罩的抗菌活性进行了量化。在培养48小时后,涂层口罩材料中的大肠杆菌和金黄色葡萄球菌活菌数量减少了100%。佩戴口罩的志愿者均未出现皮肤刺激现象。纳米颗粒作为防护服表面涂层应用时,在降低感染因子传播风险方面显示出前景。

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