Wallace L A, Young D, Brown A, Cameron J C, Ahmed S, Duff R, Carman W F, Kitchin N R E, Nguyen-Van-Tam J S, Goldberg D J
Health Protection Scotland, Clifton House, Clifton Place, Glasgow G3 7LN, UK.
Vaccine. 2005 Dec 1;23(48-49):5624-31. doi: 10.1016/j.vaccine.2005.06.034. Epub 2005 Jul 27.
In the first UK study to examine feasibility and acceptability of universal adolescent hepatitis B vaccination, the costs associated with the administration and uptake (80.2 and 89.3% for three doses and at least two doses, respectively), of a three-dose regimen in pupils in Glasgow schools (2001/2002) were measured. These data were used to estimate the economic outlay for the delivery of a routine, ongoing three-dose and two-dose hepatitis B vaccine programme in schools. Vaccine, accounting for almost 70% of the overall costs, was the largest cost item for both the pilot and routine programmes, using either regimen. However, the ongoing, two-dose regimen was the cheapest option in this analysis, irrespective of vaccine price. Cost data from this study may be useful for other countries wishing to implement a similar programme.
在英国首项研究青少年普遍接种乙型肝炎疫苗的可行性和可接受性的研究中，对格拉斯哥学校学生（2001/2002年）接种三剂次方案的接种管理及接种率（三剂次和至少两剂次的接种率分别为80.2%和89.3%）相关成本进行了测算。这些数据用于估算在学校开展常规、持续的三剂次和两剂次乙型肝炎疫苗接种计划的经济支出。无论采用哪种方案，疫苗在试点计划和常规计划中都是最大的成本项目，几乎占总成本的70%。然而，在本分析中，持续的两剂次方案是最便宜的选择，与疫苗价格无关。这项研究的成本数据可能对其他希望实施类似计划的国家有用。
