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临床惰性导致基层医疗环境中糖尿病控制不佳。

Clinical inertia contributes to poor diabetes control in a primary care setting.

作者信息

Ziemer David C, Miller Christopher D, Rhee Mary K, Doyle Joyce P, Watkins Clyde, Cook Curtiss B, Gallina Daniel L, El-Kebbi Imad M, Barnes Catherine S, Dunbar Virginia G, Branch William T, Phillips Lawrence S

机构信息

Divisions of Endocrinology and Metabolism and General Medicine, Department of Medicine, Emory University School of Medicine, Grady Health Systems, Atlanta, Georgia

The Divisions of Endocrinology and Metabolism and General Medicine, Department of Medicine, Emory University School of Medicine, Grady Health Systems, Atlanta, Georgia, and Mayo Clinic, Scottsdale, Arizona (Dr Cook)

出版信息

Diabetes Educ. 2005 Jul-Aug;31(4):564-71. doi: 10.1177/0145721705279050.

Abstract

PURPOSE

The purpose of this study was to determine whether "clinical inertia"-inadequate intensification of therapy by the provider-could contribute to high A1C levels in patients with type 2 diabetes managed in a primary care site.

METHODS

In a prospective observational study, management was compared in the Medical Clinic, a primary care site supervised by general internal medicine faculty, and the Diabetes Clinic, a specialty site supervised by endocrinologists. These municipal hospital clinics serve a common population that is largely African American, poor, and uninsured.

RESULTS

Four hundred thirty-eight African American patients in the Medical Clinic and 2157 in the Diabetes Clinic were similar in average age, diabetes duration, body mass index, and gender, but A1C averaged 8.6% in the Medical Clinic versus 7.7% in the Diabetes Clinic (P < .0001). Use of pharmacotherapy was less intensive in the Medical Clinic (less use of insulin), and when patients had elevated glucose levels during clinic visits, therapy was less than half as likely to be advanced in the Medical Clinic compared to the Diabetes Clinic (P < .0001). Intensification rates were lower in the Medical Clinic regardless of type of therapy (P < .0001), and intensification of therapy was independently associated with improvement in A1C (P < .001).

CONCLUSIONS

Medical Clinic patients had worse glycemic control, were less likely to be treated with insulin, and were less likely to have their therapy intensified if glucose levels were elevated. To improve diabetes management and glycemic control nationwide, physicians in training and generalists must learn to overcome clinical inertia, to intensify therapy when appropriate, and to use insulin when clinically indicated.

摘要

目的

本研究旨在确定“临床惰性”——医疗服务提供者治疗强化不足——是否会导致在初级保健机构接受管理的2型糖尿病患者糖化血红蛋白(A1C)水平升高。

方法

在一项前瞻性观察性研究中,对医学诊所(由普通内科教员监督的初级保健机构)和糖尿病诊所(由内分泌科医生监督的专科机构)的管理情况进行了比较。这些市立医院诊所服务于一个主要由非裔美国人、贫困人口和未参保人员组成的共同人群。

结果

医学诊所的438名非裔美国患者和糖尿病诊所的2157名患者在平均年龄、糖尿病病程、体重指数和性别方面相似,但医学诊所的A1C平均为8.6%,而糖尿病诊所为7.7%(P <.0001)。医学诊所药物治疗的使用强度较低(胰岛素使用较少),并且当患者在诊所就诊时血糖水平升高时,与糖尿病诊所相比,医学诊所治疗升级的可能性不到一半(P <.0001)。无论治疗类型如何,医学诊所的强化率都较低(P <.0001),并且治疗强化与A1C改善独立相关(P <.001)。

结论

医学诊所的患者血糖控制较差,接受胰岛素治疗的可能性较小,并且如果血糖水平升高,其治疗强化的可能性也较小。为了在全国范围内改善糖尿病管理和血糖控制,接受培训的医生和全科医生必须学会克服临床惰性,在适当的时候强化治疗,并在临床指征明确时使用胰岛素。

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