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[心肌梗死与冠状动脉瘤]

[Myocardial infarction and coronary artery aneurysm].

作者信息

Bouchiat C, Dussarat G V, Talard P

机构信息

Service de Cardiologie, Hôpital d'Instruction des Armées Sainte-Anne, Toulon Naval.

出版信息

Ann Cardiol Angeiol (Paris). 1992 Mar;41(3):145-9.

PMID:1610096
Abstract

Two cases of aneurysm of the right coronary artery are reported. These atheromatous aneurysms not associated with tight coronary stenosis were responsible for myocardial infarctions treated by early intravenous thrombolysis with a resultant limited area of necrosis. According to the literature, coronary aneurysms associated with stenosis are not rare. Aneurysms not associated with significant stenosis appear to be much less common and the prognosis of patients with such lesions would not seem to be worse than that of those with neither aneurysm nor significant coronary stenosis. From a pathophysiological standpoint, the development of local thrombosis appears to play a determinant role in terms of the clinical manifestation of these aneurysms and its prevention justifies the long term combined prescription of platelet antiaggregants and oral anticoagulants.

摘要

报告了两例右冠状动脉瘤病例。这些动脉粥样硬化性动脉瘤与严重冠状动脉狭窄无关,是导致心肌梗死的原因,通过早期静脉溶栓治疗,坏死面积有限。根据文献,伴有狭窄的冠状动脉瘤并不罕见。与明显狭窄无关的动脉瘤似乎要少见得多,此类病变患者的预后似乎并不比既无动脉瘤也无明显冠状动脉狭窄的患者更差。从病理生理学角度来看,局部血栓形成的发展似乎在这些动脉瘤的临床表现中起决定性作用,对其进行预防需要长期联合使用血小板抗聚集剂和口服抗凝剂。

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