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英国发生的输血后疟疾病例记录:与当前及拟议的献血者选择指南相关的综述

Documented cases of post-transfusion malaria occurring in England: a review in relation to current and proposed donor-selection guidelines.

作者信息

Kitchen A D, Barbara J A J, Hewitt P E

机构信息

National Transfusion Microbiology Laboratories, National Blood Service, London, UK.

出版信息

Vox Sang. 2005 Aug;89(2):77-80. doi: 10.1111/j.1423-0410.2005.00661.x.

Abstract

BACKGROUND AND OBJECTIVES

Although uncommon, five cases of transfusion-transmitted malaria have been documented in England over the last 20 years. With the reappearance onto the market of high-quality malaria antibody assays, and by utilizing the results of analysis of these five cases, it has been possible to review the donor malaria-deferral guidelines.

MATERIALS AND METHODS

Details of the five cases of post-transfusion malaria were reviewed against the proposed new donor-deferral guidelines for malaria.

RESULTS

Three of the five cases of post-transfusion malaria were directly attributable to the deferral guidelines, allowing infectious donors to be bled.

CONCLUSIONS

The proposed new guidelines will prevent further cases of transmission from semi-immune individuals.

摘要

背景与目的

尽管输血传播疟疾的情况并不常见,但在过去20年里,英国已记录了5例此类病例。随着高质量疟疾抗体检测重新上市,并通过对这5例病例的分析结果,得以重新审视献血者疟疾延期指南。

材料与方法

对照拟议的新的疟疾献血者延期指南,对5例输血后疟疾病例的详细情况进行了审查。

结果

5例输血后疟疾病例中有3例可直接归因于延期指南,使得感染的献血者得以献血。

结论

拟议的新指南将防止半免疫个体进一步传播病例。

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