Tetteh Ato Kwamena, Arthur Sadick, Bram Prince, Baffe Charles, Aglagoh Godsway
Metropolitan Hospital, Laboratory Department, P. O. Box 174, Cape Coast, Ghana.
Cape Coast Teaching Hospital, Laboratory Department, P. O. Box CT 1363, Cape Coast, Ghana.
J Trop Med. 2023 Jan 4;2023:8685482. doi: 10.1155/2023/8685482. eCollection 2023.
Malaria is an important transfusion-associated infection in many parts of the world, particularly in sub-Saharan Africa, where it is endemic. We studied the prevalence of malaria parasites among blood donors in the Cape Coast Metropolitan Area.
A malaria parasite examination was added to the blood donor screening protocol for 240 voluntary and replacement blood donors (224 males and 16 females) between December 2020 and July 2021.
Overall, 2.5% (6/240) had trophozoites detected in their blood sample. The remaining had no parasites detected. Four of the 148 who passed the blood donor screening tests were infected. The remaining two with malaria parasites failed one screening test. These included one donor with "hepatitis + " and another with "syphilis + " parasite coinfection. All blood donors who had malaria parasites detected in their blood were males. Most donors, 45.8% (110/240), were in the 26-35 age group, with the highest prevalence of 1.3% (3/240). Blood group O was predominant (75.0%, 180/240), followed by B (12.9%, 31/240), A (11.3%, 27/240), and AB (0.8%, 2/240). All malaria parasites detected were among individuals with blood group O. Moreover, 96.3% (231/240) were rhesus-positive and had the highest prevalence of 2.1% (5/240).
Screening of blood donors in Ghana does not include malaria, although there is the potential for transmission through blood products. Malaria transmission via blood transfusion remains an issue of public health concern, as indicated in the results of this current study. We recommend studies on malaria prevention, pretransfusion and posttransfusion, and pathogen reduction technology.
疟疾是世界上许多地区，尤其是撒哈拉以南非洲流行地区重要的与输血相关的感染。我们研究了海岸角都会区献血者中疟原虫的流行情况。
在2020年12月至2021年7月期间，对240名自愿和替代献血者（224名男性和16名女性）的献血者筛查方案增加了疟原虫检查。
总体而言，2.5%（6/240）的血液样本中检测到滋养体。其余未检测到寄生虫。在通过献血者筛查测试的148人中，有4人被感染。其余两名携带疟原虫的献血者有一项筛查测试未通过。其中包括一名“肝炎阳性”的献血者和另一名“梅毒阳性”的寄生虫合并感染献血者。所有血液中检测到疟原虫的献血者均为男性。大多数献血者，45.8%（110/240），年龄在26 - 35岁组，患病率最高为1.3%（3/240）。O型血占主导（75.0%，180/24），其次是B型（12.9%，31/240），A型（11.3%，27/240），AB型（0.8%，2/24）。所有检测到的疟原虫均在O型血个体中。此外，96.3%（231/240）为恒河猴阳性，患病率最高为2.1%（5/240）。
加纳的献血者筛查不包括疟疾，尽管存在通过血液制品传播的可能性。正如本研究结果所示，通过输血传播疟疾仍然是一个公共卫生问题。我们建议开展关于疟疾预防、输血前和输血后以及病原体灭活技术的研究。
