Hall Gillian, Kirk Martyn D, Becker Niels, Gregory Joy E, Unicomb Leanne, Millard Geoffrey, Stafford Russell, Lalor Karin
National Centre for Epidemiology and Population Health, Australian National University, Canberra, Australian Capital Territory, Australia.
Emerg Infect Dis. 2005 Aug;11(8):1257-64. doi: 10.3201/eid1108.041367.
We estimated for Australia the number of cases, hospitalizations, and deaths due to foodborne gastroenteritis in a typical year, circa 2000. The total amount of infectious gastroenteritis was measured by using a national telephone survey. The foodborne proportion was estimated from Australian data on each of 16 pathogens. To account for uncertainty, we used simulation techniques to calculate 95% credibility intervals (CrI). The estimate of incidence of gastroenteritis in Australia is 17.2 million (95% confidence interval 14.5-19.9 million) cases per year. We estimate that 32% (95% CrI 24%-40%) are foodborne, which equals 0.3 (95% CrI 0.2-0.4) episodes per person, or 5.4 million (95% CrI 4.0-6.9 million) cases annually in Australia. Norovirus, enteropathogenic Escherichia coli, Campylobacter spp., and Salmonella spp. cause the most illnesses. In addition, foodborne gastroenteritis causes approximately 15,000 (95% CrI 11,000-18,000) hospitalizations and 80 (95% CrI 40-120) deaths annually. This study highlights global public health concerns about foodborne diseases and the need for standardized methods, including assessment of uncertainty, for international comparison.
我们估算了2000年前后澳大利亚每年因食源性肠胃炎导致的病例数、住院数和死亡数。通过全国电话调查来测定感染性肠胃炎的总数。食源性肠胃炎的比例根据澳大利亚16种病原体各自的数据进行估算。为了考虑不确定性,我们使用模拟技术计算95%的可信度区间(CrI)。澳大利亚肠胃炎发病率的估算值为每年1720万例(95%置信区间为1450万 - 1990万例)。我们估计32%(95% CrI为24% - 40%)的病例是食源性的,这相当于每人每年0.3次(95% CrI为0.2 - 0.4次)发病,即澳大利亚每年有540万例(95% CrI为400万 - 690万例)。诺如病毒、致病性大肠杆菌、弯曲杆菌属和沙门氏菌属导致的发病最多。此外,食源性肠胃炎每年导致约15000例(95% CrI为11000 - 18000例)住院和80例(95% CrI为40 - 120例)死亡。这项研究凸显了全球对食源性疾病的公共卫生关注,以及对包括不确定性评估在内的标准化方法进行国际比较的必要性。