Dolianitis Con, Kelly John, Wolfe Rory, Simpson Pamela
Victorian Melanoma Service, Department of Dermatology, Alfred Hospital, Melbourne, Victoria, Australia.
Arch Dermatol. 2005 Aug;141(8):1008-14. doi: 10.1001/archderm.141.8.1008.
To assess 4 dermoscopy methods in a nonexpert setting.
Sixty-one medical practitioners, mainly primary care physicians in Australia, were trained in 4 dermoscopy algorithms. Participants then assessed macroscopic and dermoscopic images of 40 melanocytic skin lesions. Each of the dermoscopic images was assessed with pattern analysis, the 7-point checklist, the ABCD rule, and the Menzies method.
The Menzies method showed the highest sensitivity, 84.6%, for the diagnosis of melanoma, followed by the 7-point checklist (81.4%), the ABCD rule (77.5%), pattern analysis (68.4%), and assessment of a macroscopic image (60.9%). Pattern analysis and assessment of the macroscopic image showed the highest specificity, 85.3% and 85.4%, respectively. The ABCD rule showed a specificity of 80.4%; the Menzies method, 77.7%; and the 7-point checklist, 73%. The Menzies method had a diagnostic accuracy of 81.1%; the ABCD rule, 79.0%; the 7-point checklist, 77.2%; pattern analysis, 76.8%; and clinical assessment, 73.2%.
All algorithms performed well in the hands of relatively inexpert practitioners who had undertaken self-guided training provided on compact disc. The Menzies method showed the highest diagnostic accuracy and sensitivity for melanoma diagnosis and was preferred by study participants.
在非专业环境中评估4种皮肤镜检查方法。
61名医学从业者(主要是澳大利亚的初级保健医生)接受了4种皮肤镜检查算法的培训。参与者随后对40例黑素细胞性皮肤病变的宏观和皮肤镜图像进行评估。每种皮肤镜图像均采用模式分析、7分检查表、ABCD规则和门齐斯方法进行评估。
门齐斯方法对黑色素瘤诊断的敏感性最高,为84.6%,其次是7分检查表(81.4%)、ABCD规则(77.5%)、模式分析(68.4%)和宏观图像评估(60.9%)。模式分析和宏观图像评估的特异性最高,分别为85.3%和85.4%。ABCD规则的特异性为80.4%;门齐斯方法为77.7%;7分检查表为73%。门齐斯方法的诊断准确率为81.1%;ABCD规则为79.0%;7分检查表为77.2%;模式分析为76.8%;临床评估为73.2%。
在接受了光盘上提供的自我指导培训的相对非专业的从业者手中,所有算法都表现良好。门齐斯方法对黑色素瘤诊断显示出最高的诊断准确率和敏感性,并且受到研究参与者的青睐。