Spurling Geoffrey, Lucas Romuald, Doust Jenny
University of Queensland, Brisbane, Australia; Médecins Sans Frontières, Paris, France.
Am J Trop Med Hyg. 2005 Aug;73(2):307-8.
The objective of this study is to determine if a Chagas disease protocol starting with a serological survey is as reliable at identifying insect-infested areas as one using the gold standard entomological survey. The study found that health center areas infested with Rhodnius prolixus were identified using a threshold seroprevalence of 0.1%. The serological survey took half the time and was 30% less expensive than the entomological survey. Developing countries with limited resources may find this strategy useful in combating Chagas disease. This strategy also identifies seropositive children, which facilitates their treatment.
本研究的目的是确定从血清学调查开始的恰加斯病方案在识别昆虫滋生区域方面是否与使用金标准昆虫学调查的方案一样可靠。研究发现,使用0.1%的血清阳性率阈值可识别出感染克氏锥蝽的卫生中心区域。血清学调查耗时仅为昆虫学调查的一半,成本比昆虫学调查低30%。资源有限的发展中国家可能会发现这一策略在对抗恰加斯病方面有用。该策略还能识别血清学阳性儿童,便于对他们进行治疗。