Feliciangeli M Dora, Sánchez-Martín Maria J, Suárez Benny, Marrero Rosalba, Torrellas Annhymariet, Bravo Arturo, Medina Mehudy, Martínez Cinda, Hernandez Mayeli, Duque Neidi, Toyo José, Rangel Roberto
Facultad de Ciencias de la Salud, Centro Nacional de Referencia de Flebótomos y Otros Vectores, Universidad de Carabobo, Maracay, Venezuela.
Am J Trop Med Hyg. 2007 May;76(5):915-21.
This study attempted to quantify the transmission of Trypanosoma cruzi in children less than 15 years of age in Barinas State, Venezuela and investigate risk factors for infection. Among 3,296 children, 4 (0.12%) were seropositive. The mother of one child also was also seropositive, which suggested that congenital transmission is a possible risk factor for Chagas disease in this area. Seroprevalence among the dwellers of 10 localities was 3.3%. Rhodnius prolixus was detected in 7 localities and in 8% of 125 dwellings. A multivariate logistic regression model showed that infection was associated with age, a dirt floor, and distance from houses to palm trees. The risk of infection is increased by the presence of adventitious sylvatic R. prolixus and transient or residual colonies. Insecticide spraying does not seem justified in this scenario, a finding that was also observed in other Latin American countries. New methods are therefore needed for Chagas disease control programs.
本研究试图对委内瑞拉巴里纳斯州15岁以下儿童中克氏锥虫的传播进行量化，并调查感染的风险因素。在3296名儿童中，4名（0.12%）血清呈阳性。其中一名儿童的母亲血清也呈阳性，这表明先天性传播可能是该地区恰加斯病的一个风险因素。10个地区居民的血清阳性率为3.3%。在7个地区以及125所住宅中的8%检测到了长红猎蝽。多变量逻辑回归模型显示，感染与年龄、泥土地面以及房屋到棕榈树的距离有关。偶然出现的野生型长红猎蝽以及短暂或残留的虫群会增加感染风险。在这种情况下，喷洒杀虫剂似乎没有道理，其他拉丁美洲国家也观察到了这一现象。因此，恰加斯病控制项目需要新的方法。
