Boztuğ N, Bigat Z, Ertok E, Erman M
Department of Anaesthesiology and Reanimation, Akdeniz University Medical Faculty, Antalya, Turkey.
J Int Med Res. 2005 Jul-Aug;33(4):365-71. doi: 10.1177/147323000503300401.
We evaluated the effects of low-dose intrathecal ropivacaine with or without fentanyl for arthroscopic knee surgery. Fifty patients were randomized in equal groups to receive an intrathecal solution (3 ml) containing either 10 mg isobaric ropivacaine or 8 mg isobaric ropivacaine plus 25 pg fentanyl. Complete motor blockade occurred in 22 patients (88%) in both groups. The time taken to reach sensory blockade to T10 and total motor blockade was shorter in the ropivacaine-treated group, but differences were not statistically significant. The duration of sensory and motor blockade was shorter in the ropivacaine plus fentanyl-treated group. The cephalad spread of sensory blockade was higher with ropivacaine than with ropivacaine plus fentanyl. We conclude that although 25 microg fentanyl added to 8 mg ropivacaine provided shorter motor and sensory blockade durations than 10 mg ropivacaine alone, small doses of ropivacaine plus fentanyl can be used safely for arthroscopic knee surgery.
我们评估了低剂量鞘内注射罗哌卡因联合或不联合芬太尼用于膝关节镜手术的效果。50例患者被随机分为两组,分别接受含10mg等比重罗哌卡因的鞘内溶液(3ml)或8mg等比重罗哌卡因加25μg芬太尼的鞘内溶液。两组均有22例患者(88%)出现完全运动阻滞。罗哌卡因治疗组达到T10感觉阻滞和完全运动阻滞的时间较短,但差异无统计学意义。罗哌卡因加芬太尼治疗组的感觉和运动阻滞持续时间较短。罗哌卡因组感觉阻滞的头端扩散高于罗哌卡因加芬太尼组。我们得出结论,虽然8mg罗哌卡因加25μg芬太尼的运动和感觉阻滞持续时间比单独使用10mg罗哌卡因短,但小剂量罗哌卡因加芬太尼可安全用于膝关节镜手术。