[停用阿司匹林和类固醇后并发原发性抗磷脂综合征的急性心肌梗死]

[Acute myocardial infarction complicating primary antiphospholipid syndrome after aspirin and steroids withdrawal].

作者信息

Wahbi K, Salengro E, Galicier L, Guillevin L, Spaulding C, Weber S, Meune C

机构信息

Service de cardiologie, hôpital Cochin, université René-Descartes, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France.

出版信息

Ann Cardiol Angeiol (Paris). 2005 Aug;54(4):212-5. doi: 10.1016/j.ancard.2005.05.019.

DOI:10.1016/j.ancard.2005.05.019

PMID:16104622

Abstract

A 24-year-old woman, with known antiphospholid antibodies (APS), presented with an acute myocardial infarction (AMI) that occurred three months after delivery. No risk factors for arteriosclerosis and no past history of arterial/venous thrombosis were noted. During pregnancy, aspirin prophylaxis was prescribed and followed by steroids after caesarian section. Steroids withdrawal was followed by AMI. Immediate coronary angiography revealed thrombotic occlusion of the left descending coronary artery; PTCA was successfully performed. She was discharged with an antiplatelet and anticoagulant regimen. No recurrent coronary event occurred during follow-up.

摘要

一名24岁已知抗磷脂抗体（APS）的女性，在分娩后三个月出现急性心肌梗死（AMI）。未发现动脉硬化的危险因素，也无动脉/静脉血栓形成的既往史。孕期给予阿司匹林预防，剖宫产术后给予类固醇治疗。停用类固醇后发生急性心肌梗死。急诊冠状动脉造影显示左前降支冠状动脉血栓性闭塞；成功进行了经皮冠状动脉腔内血管成形术（PTCA）。她出院时接受抗血小板和抗凝治疗方案。随访期间未发生复发性冠状动脉事件。