Siu Jason, Baxendale Ian R, Lewthwaite Russell A, Ley Steven V
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Org Biomol Chem. 2005 Sep 7;3(17):3140-60. doi: 10.1039/b503778f. Epub 2005 Jul 27.
In this paper we wish to report on a variety of expedient chemical transformations and purifications achieved via a generic "catch and release" methodology, based on a synthetically inert bipyridyl chelating tag that can be selectively captured with a resin-bound copper(II) species. Utilising this approach we are able to derive many of the same benefits associated with both solid phase synthesis and supported reagent methods.
在本文中，我们希望报告通过一种通用的“捕获与释放”方法实现的各种便捷的化学转化和纯化过程，该方法基于一种合成惰性的联吡啶螯合标签，它可以被树脂结合的铜（II）物种选择性捕获。利用这种方法，我们能够获得与固相合成和负载试剂方法相关的许多相同益处。
