Mäkelä J P, Hari R
Low Temperature Laboratory, Helsinki University of Technology, Espoo, Finland.
Neuroreport. 1992 Jan;3(1):94-6. doi: 10.1097/00001756-199201000-00025.
Auditory evoked magnetic fields were recorded with a 24-SQUID magnetometer on a patient with a vascular lesion in the right auditory cortex and its vicinity. The contralateral transient 100 ms response (N100m) was absent over the damaged side, with no recovery within 16 months. Responses were normal over the healthy side. The responses to a binaural click train where interaural delays caused the perception of a shifting sound source; responses were again normal over the left side. Ipsilateral tones elicited N100m over the normal hemisphere but with smaller amplitude and longer latency than in healthy subjects. We suggest that ipsilateral responses are triggered by ipsilateral afferents but are significantly modified by excitatory callosal connections which did not work in our patient.
使用24通道超导量子干涉仪磁力计对一名右侧听觉皮层及其附近存在血管病变的患者进行听觉诱发磁场记录。在受损侧未记录到对侧短暂100毫秒反应(N100m),且在16个月内未恢复。健康侧的反应正常。对于双耳点击序列,当双耳延迟导致声源移动感知时,左侧反应再次正常。同侧音调在正常半球诱发N100m,但与健康受试者相比,其振幅较小且潜伏期较长。我们认为同侧反应由同侧传入神经触发,但在我们的患者中,兴奋性胼胝体连接未起作用,从而对同侧反应产生了显著影响。