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[不同易感性大鼠在制动-冷应激下胃黏膜损伤时胃泌素反应的特点]

[Features of gastrin reaction in rats with different susceptibilities to gastric mucosa lesions in immobilization-cold stress].

作者信息

Popovich I L, Butusova I A, Ivasivka S V, Iaramenko M S

出版信息

Biull Eksp Biol Med. 1992 Feb;113(2):126-7.

PMID:1611050
Abstract

The connection between the character of gastrin and acid reactions and visible morphological changes of gastric mucosa in immobilising-cold stress was studied in the experiments on mongrel rats. It is established that in the rats the fundal gastric mucosa is resistant to the disturbing action of the immobilising-cold stress. The post-stress gastrin contents in the antrum and duodenum mucosa is higher and in the serum lower than in rats with ulceration. The rats with the stress erosions have the intermediate position. The acid factor didn't play the significant role in the ulcerogenesis because its value didn't overstep the limits established in the extradigestive period.

摘要

在杂种大鼠实验中,研究了胃泌素特性与酸反应以及固定冷应激时胃黏膜可见形态变化之间的联系。已确定大鼠胃底黏膜对固定冷应激的干扰作用具有抗性。应激后胃窦和十二指肠黏膜中的胃泌素含量高于溃疡大鼠,而血清中的胃泌素含量低于溃疡大鼠。有应激性糜烂的大鼠处于中间位置。酸因素在溃疡形成过程中未起显著作用,因为其值未超出消化外期确定的范围。

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