Teubner Michael D, Nixon John B, Rasser Paul E, Bottema Murk J, Clark C Richard
Applied Mathematics, School of Mathematical Sciences, University of Adelaide, Australia.
Brain Topogr. 2005 Summer;17(4):197-205. doi: 10.1007/s10548-005-6029-x.
Neural activity within the human brain produces electrical potentials that are transmitted through the various tissues of the head to the scalp. A three-dimensional finite difference model has been applied to simulate this process and used as the basis for an inverse model, wherein known potentials on the scalp are used to locate sources of neural activity within the brain. The inverse model uses linear and nonlinear response functions, together with nonlinear regression to determine the source location. The model has been applied to three different simulations, and in each case was able to locate the source using a combination of linear and nonlinear response functions.
人类大脑内的神经活动会产生电势，这些电势通过头部的各种组织传输到头皮。一个三维有限差分模型已被用于模拟这一过程，并作为逆模型的基础，在逆模型中，头皮上已知的电势被用于定位大脑内神经活动的源头。该逆模型使用线性和非线性响应函数，以及非线性回归来确定源头位置。该模型已应用于三种不同的模拟，并且在每种情况下都能够通过线性和非线性响应函数的组合来定位源头。
