Byrne Thomas E
Department of Radiation Oncology, Thompson Cancer Survival Center, Knoxville, TN 37916, USA.
Med Dosim. 2005 Fall;30(3):155-61. doi: 10.1016/j.meddos.2005.03.005.
The motion of the prostate gland can influence the efficacy of radiation therapy. This article examines the literature concerning prostate gland motion with considerations for the treatment of cancer. The objectives of this review include providing radiation oncologists, medical physicists, and dosimetrists with data to assist in determining the best treatment adaptation for individual patients. The prostate gland is not a static structure, but rather a dynamic structure and this should be a consideration in the treatment protocol. The treatment planning personnel must add a margin to the clinical treatment volume (CTV) radiation field to account for prostate motion and patient setup errors resulting in a planning treatment volume (PTV). The movement of the prostate in a radiation field with a small margin to protect the anterior rectum may allow the posterior aspect of the gland to escape the prescribed dose. Thus, an understanding of potential prostate movements in radiation therapy is critical to achieve tumor control and minimize radiation complications in patients.
前列腺的运动可影响放射治疗的疗效。本文探讨了有关前列腺运动的文献，并考虑了癌症治疗的相关因素。本综述的目的包括为放射肿瘤学家、医学物理学家和剂量测定师提供数据，以协助确定针对个体患者的最佳治疗方案。前列腺不是一个静态结构，而是一个动态结构，这一点在治疗方案中应予以考虑。治疗计划人员必须在临床靶区（CTV）辐射野周围增加一个边界，以考虑前列腺运动和患者摆位误差，从而形成计划靶区（PTV）。在为保护直肠前部而设置边界较小的辐射野中，前列腺的移动可能会使腺体后部无法获得规定剂量。因此，了解放射治疗中前列腺的潜在移动对于实现肿瘤控制和将患者的放射并发症降至最低至关重要。
