Rizk N N
Acta Cytol. 1979 Mar-Apr;23(2):156-62.
The surface features and behavior of the connective tissue cell in normal areas and in healing incisions of the aponeuroses of the abdominal wall of the albino rat were studied with the scanning electron microscope (SEM). The normal cell is smooth, oval or triangular in outline and has a generally rounded surface and very short or no cell processes. The behavior of the fibroblasts and the condition of the fibers in and around the wounds were visualized. Shortly after the incision, the fibroblasts accumulated around the wound, possibly by increased cell division. At the site of the incision the cells responded by a self-protective mechanism in which they withdrew their processes and acquired a spheroid form. During the maximum period of a fibrillogenesis the fibroblasts enlarged, acquired a fusiform outline and long processes, exhibited a roughened surface and were surrounded with small rounded cell particles polymerizing into fine fibrils. The process of collagen secretion and three stages of collagen maturation were visualized. Some abnormal cells were seen; they could be evidence of merocrine or holocrine mode of secretion or possibly signs of cell senility.
用扫描电子显微镜（SEM）研究了白化大鼠腹壁腱膜正常区域和愈合切口处结缔组织细胞的表面特征和行为。正常细胞表面光滑，轮廓呈椭圆形或三角形，表面通常呈圆形，细胞突起很短或没有。观察了成纤维细胞的行为以及伤口内和周围纤维的状况。切口后不久，成纤维细胞在伤口周围聚集，可能是通过细胞分裂增加所致。在切口部位，细胞通过一种自我保护机制做出反应，即它们缩回突起并呈球状。在纤维形成的高峰期，成纤维细胞增大，呈梭形轮廓并具有长突起，表面粗糙，周围有小圆形细胞颗粒聚合成细纤维。观察到了胶原蛋白分泌过程和胶原蛋白成熟的三个阶段。还观察到一些异常细胞；它们可能是局部分泌或全部分泌模式的证据，也可能是细胞衰老的迹象。
