Luck C A
Heatherwood Hospital, Ascot, Berkshire.
BMJ. 1992 Jun 6;304(6840):1474-8. doi: 10.1136/bmj.304.6840.1474.
To evaluate the effectiveness of routine ultrasound scanning at 19 weeks' gestation in an unselected population in terms of accuracy of detection of fetal structural abnormality and the effect on obstetric and neonatal care.
Prospective study over four years. Scans performed by radiographers with overall supervision by a radiologist.
Ultrasound department of district general hospital.
All pregnant women were offered scans; 8523 of 8849 (96%) accepted.
Information obtained from hospital records, genetic analysis, and post-mortem findings.
166 fetal anomalies occurred; 140 were detected at 19 weeks (sensitivity 85%; specificity 99.9%). In 27 cases fetuses were shown to have severely crippling or lethal abnormalities; termination of pregnancy was requested in 25. Early diagnosis influenced timing and place of delivery in babies with severe cardiac or gastrointestinal anomalies.
Scanning at 19 weeks with availability of termination can reduce perinatal morbidity and mortality. Scanning can be performed in a general ultrasound department with adequate counselling facilities and close cooperation between radiographers, midwives, obstetricians, paediatricians, and the radiologist.
在未经过挑选的人群中,评估妊娠19周时进行常规超声扫描在检测胎儿结构异常的准确性以及对产科和新生儿护理的影响方面的有效性。
为期四年的前瞻性研究。扫描由放射技师进行,全程接受放射科医生的监督。
地区综合医院的超声科。
向所有孕妇提供扫描服务;8849名孕妇中有8523名(96%)接受了扫描。
从医院记录、基因分析和尸检结果中获取的信息。
共出现166例胎儿异常;19周时检测出140例(灵敏度85%;特异度99.9%)。在27例病例中,胎儿显示有严重致残或致命异常;25例请求终止妊娠。早期诊断影响了患有严重心脏或胃肠道异常婴儿的分娩时间和地点。
在可进行终止妊娠的情况下,妊娠19周时进行扫描可降低围产期发病率和死亡率。扫描可在具备适当咨询设施且放射技师、助产士、产科医生、儿科医生和放射科医生密切合作的普通超声科进行。