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Prenatal detection of congenital heart disease: factors affecting obstetric management and survival.

作者信息

Crawford D C, Chita S K, Allan L D

机构信息

British Heart Foundation Centre for Perinatal Cardiology, United Medical School, Guy's Hospital, London, England.

出版信息

Am J Obstet Gynecol. 1988 Aug;159(2):352-6. doi: 10.1016/s0002-9378(88)80083-8.

DOI:10.1016/s0002-9378(88)80083-8
PMID:3407692
Abstract

Our recent experience in the diagnosis and management of fetal congenital heart disease is presented. During an 18-month period from January 1985 to June 1986, 1757 fetal echocardiograms were performed on a total of 989 antenatal patients. Cardiac anomalies were accurately predicted in 74 cases, 34 of which were associated with extracardiac or chromosomal anomalies. Twenty-three pregnancies were electively terminated. Currently the survival rate for ongoing pregnancies is 17%. A false negative diagnosis was made in 16 cases, the majority involving minor anomalies with a good prognosis and a survival rate of 81%. Prenatal detection of congenital heart disease places the fetus at high risk for chromosomal and extracardiac anomalies. Congenital heart disease detectable during pregnancy is usually severe and associated with a poor long-term prognosis. Termination of the pregnancy may be a reasonable option if a severe anomaly is detected early in pregnancy.

摘要

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