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Differences in the prevalence of PTPN11 mutations in FAB M5 paediatric acute myeloid leukaemia.

作者信息

Goemans B F, Zwaan C M, Martinelli S, Harrell P, de Lange D, Carta C, Reinhardt D, Hählen K, Creutzig U, Tartaglia M, Heinrich M C, Kaspers G J L

出版信息

Br J Haematol. 2005 Sep;130(5):801-3. doi: 10.1111/j.1365-2141.2005.05685.x.

DOI:10.1111/j.1365-2141.2005.05685.x
PMID:16115145
Abstract
摘要

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Differences in the prevalence of PTPN11 mutations in FAB M5 paediatric acute myeloid leukaemia.儿童急性髓系白血病FAB M5型中PTPN11突变发生率的差异
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Mutations of PTPN11 are rare in adult myeloid malignancies.蛋白酪氨酸磷酸酶非受体型11（PTPN11）的突变在成人髓系恶性肿瘤中罕见。
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PTPN11 mutations in pediatric patients with acute myeloid leukemia: results from the Children's Cancer Group.儿童急性髓系白血病患者的PTPN11突变：儿童癌症研究组的结果
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Mutations in PTPN11 are rare in adult myelodysplastic syndromes and acute myeloid leukemia.蛋白酪氨酸磷酸酶非受体型11（PTPN11）的突变在成人骨髓增生异常综合征和急性髓系白血病中较为罕见。
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