偏头痛和紧张型头痛的预后：一项基于人群的随访研究。

Prognosis of migraine and tension-type headache: a population-based follow-up study.

作者信息

Lyngberg Ann Christine, Rasmussen Birthe Krogh, Jørgensen Torben, Jensen Rigmor

机构信息

Research Centre for Prevention and Health, Glostrup University Hospital, Nordre Ringvej 57, Building 84/85, DK-2600 Glostrup, Denmark.

出版信息

Neurology. 2005 Aug 23;65(4):580-5. doi: 10.1212/01.wnl.0000172918.74999.8a.

DOI:10.1212/01.wnl.0000172918.74999.8a

PMID:16116119

Abstract

OBJECTIVE

To determine the prognosis of migraine and tension-type headache and to identify prognostic factors.

METHODS

Of 740 persons (aged 25 to 64 years) examined in a 1989 Danish cross-sectional headache study, 673 were eligible for follow-up in 2001. All interviews at baseline and at follow-up were conducted by medical doctors and based on the 1988 IHS-criteria.

RESULTS

A total of 549 persons (81.6%) participated in the follow-up study. Of 64 migraineurs at baseline, 42% had experienced remission, 38% had low migraine frequency, and 20% had more than 14 migraine days per year (poor outcome) at follow-up. Poor outcome was associated with high migraine frequency at baseline and age at onset younger than 20 years. Among 146 subjects with frequent episodic tension-type headache and 15 with chronic tension-type headache at baseline, 45% experienced infrequent or no tension-type headache (remission), 39% had frequent episodic tension-type headache, and 16% experienced chronic tension-type headache (poor outcome) at follow-up. Poor outcome was associated with baseline chronic tension-type headache, coexisting migraine, not being married, and sleeping problems.

CONCLUSIONS

The prognosis of migraine, frequent episodic tension-type headache, and chronic tension-type headache was favorable.

摘要

目的

确定偏头痛和紧张型头痛的预后并识别预后因素。

方法

在1989年丹麦一项横断面头痛研究中接受检查的740人（年龄在25至64岁之间）中，673人符合2001年随访条件。基线和随访时的所有访谈均由医生进行，并基于1988年国际头痛协会（IHS）标准。

结果

共有549人（81.6%）参与了随访研究。在基线时的64名偏头痛患者中，42%经历了缓解，38%偏头痛发作频率较低，20%在随访时每年偏头痛天数超过14天（预后不良）。预后不良与基线时偏头痛发作频率高以及发病年龄小于20岁有关。在基线时146名发作性紧张型头痛频繁和15名慢性紧张型头痛患者中，45%经历了发作性紧张型头痛不频繁或无发作性紧张型头痛（缓解），39%有发作性紧张型头痛频繁，16%在随访时经历慢性紧张型头痛（预后不良）。预后不良与基线慢性紧张型头痛、并存偏头痛、未婚以及睡眠问题有关。