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Comparative sorption of clomipramine, viloxazine, and maprotiline hydrochlorides in polyvinylchloride bags and glass vials.

作者信息

Airaudo C B, Bianchi C, Verdier M, Gayte-Sorbier A

机构信息

Pharmacy of Valvert Hospital, Marseilles, France.

出版信息

Clin Ther. 1992 Mar-Apr;14(2):192-5.

PMID:1611643
Abstract

The sorption of clomipramine, viloxazine, and maprotiline hydrochlorides was studied comparatively in polyvinylchloride (PVC) bags and glass flasks for up to 72 hours. When stored in glass flasks, no decrease in concentration was observed for any of the three drugs, either in dextrose or sodium chloride isotonic solution. When stored in PVC bags, a slight loss (about 7% within 72 hours), was noted for clomipramine hydrochloride in both isotonic solutions, but not for the other two drugs.

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