Vijayakumar V, Blend M J, Johnson D, Schnobrich K, Golick J
Division of Nuclear Medicine, Humana Hospital-Michael Reese, Chicago, Illinois.
Clin Nucl Med. 1992 Mar;17(3):180-4. doi: 10.1097/00003072-199203000-00005.
The usefulness of radioimmunoscintigraphy with In-111 labeled MoAb B72.3 is illustrated in this case report of a patient with an aggressive cancer of the ascending colon. When used in conjunction with CT, ultrasound examination, and MRI, radioimmunoscintigraphy improved the specificity of these other imaging modalities, although the patient's serum CEA and TAG-72 levels remained within the normal ranges. In addition, MoAb imaging demonstrated superiority over CT in identifying an additional unsuspected lesion. Detection of occult disease by imaging modalities with or without elevated serum CEA levels is discussed.
本病例报告展示了用铟 - 111标记的单克隆抗体B72.3进行放射免疫闪烁显像在一名升结肠癌侵袭性癌症患者中的应用价值。当与CT、超声检查和MRI联合使用时，放射免疫闪烁显像提高了这些其他成像方式的特异性，尽管患者的血清癌胚抗原（CEA）和TAG - 72水平仍在正常范围内。此外，单克隆抗体成像在识别另一个未被怀疑的病变方面显示出优于CT的优势。本文还讨论了通过成像方式检测隐匿性疾病（无论血清CEA水平是否升高）的情况。
