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扩大秀丽隐杆线虫的神经系统:一只猿等同于3300万条线虫吗?

Scaling up the nervous system of Caenorhabditis elegans: is one ape equal to 33 million worms?

作者信息

Yamamoto W S, Achacoso T B

机构信息

Department of Computer Medicine, George Washington University School of Medicine, Washington, D.C. 20037.

出版信息

Comput Biomed Res. 1992 Jun;25(3):279-91. doi: 10.1016/0010-4809(92)90043-a.

DOI:10.1016/0010-4809(92)90043-a
PMID:1611892
Abstract

Although vastly different, both the mammalian brain and the nematode Caenorhabditis elegans' nervous system must contribute critically to assure survival. Two quantitative conditions which place bounds on networks for connectedness and stability are tested on the published neural network of C. elegans and fit. Consideration of networks scaled up to mammalian size and confined between these bounds suggests that perhaps, the entire spectrum of brain size may be built between these bounds. Further consequences of increasing brain size relate to the trade-off between complexity, providing internal resistance to individual damage, and redundancy of population, as survival mechanisms.

摘要

尽管哺乳动物的大脑和线虫秀丽隐杆线虫的神经系统存在巨大差异,但二者对于确保生存都起着至关重要的作用。在已发表的秀丽隐杆线虫神经网络上测试并拟合了两个对网络连通性和稳定性构成限制的定量条件。对按哺乳动物规模扩大并限制在这些界限之间的网络进行考量表明,也许整个脑容量范围都可以在这些界限之间构建。脑容量增加的进一步影响涉及复杂性(为个体损伤提供内在抵抗力)与群体冗余(作为生存机制)之间的权衡。

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