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Comparative pharmacology of three new nitrosourea analogues: RFCNU, RPCNU, and chlorozotocin. I. Oncostatic effects in mice.

作者信息

Hayat M, Bourut C, Chenu E, Montero J L, Imbach J L, MacDonald J S, Mathé G

出版信息

Cancer Chemother Pharmacol. 1979;3(4):217-21. doi: 10.1007/BF00254734.

DOI:10.1007/BF00254734
PMID:161207
Abstract
摘要

相似文献

1
Comparative pharmacology of three new nitrosourea analogues: RFCNU, RPCNU, and chlorozotocin. I. Oncostatic effects in mice.三种新型亚硝基脲类似物：RFCNU、RPCNU和氯脲霉素的比较药理学。I. 对小鼠的抑癌作用
Cancer Chemother Pharmacol. 1979;3(4):217-21. doi: 10.1007/BF00254734.
2
Comparative analysis of the immunopharmacological properties of three new nitrosourea analogues: RPCNU, RFCNU and Chlorozotocin.三种新型亚硝基脲类似物：RPCNU、RFCNU和氯脲霉素的免疫药理学特性比较分析。
Int J Immunopharmacol. 1983;5(3):201-10. doi: 10.1016/0192-0561(83)90057-7.
3
Comparison of the experimental antitumor activities of three nitrosourea derivatives chlorozotocin, RFCNU and CNCC encapsulated in liposomes with those in the free state.
Oncology. 1985;42(2):122-8. doi: 10.1159/000226014.
4
[Phase II study of 3 new nitrosoureas, 1 American (chlorozotocin) and 2 French (RFCNU and RPCNU)].
Sem Hop. 1982 Sep 16;58(33):1867-71.
5
A new nitrosourea derivative TA-077, 1-(2-chloroethyl)-3-isobutyl-3-(beta-maltosyl)-1-nitrosourea. I. Comparative study on antitumor activity.一种新的亚硝基脲衍生物TA - 077，1 -（2 - 氯乙基）- 3 - 异丁基 - 3 -（β - 麦芽糖基）- 1 - 亚硝基脲。I. 抗肿瘤活性的比较研究。
Cancer Chemother Pharmacol. 1982;9(3):134-9. doi: 10.1007/BF00257741.
6
Effects of three new nitrosourea analogs (CNCC, RFCNU and chlorozotocin) on in vivo destruction of L 1210 leukemia cells and on the immune response.
Chemotherapy. 1986;32(2):131-7. doi: 10.1159/000238404.
7
Chlorozotocin. Mechanism of reduced bone marrow toxicity in mice.氯脲霉素。小鼠骨髓毒性降低的机制。
J Clin Invest. 1979 Oct;64(4):1103-11. doi: 10.1172/JCI109549.
8
Contributions of nitrosoureas to cancer treatment.亚硝基脲类药物在癌症治疗中的作用。
Cancer Treat Rep. 1986 Jan;70(1):31-41.
9
Pharmacology of chlorozotocin Nsc-178248), a new nitrosourea antitumor agent.新型亚硝基脲类抗肿瘤药物氯脲霉素（Nsc - 178248）的药理学
Cancer Treat Rep. 1976 Jun;60(6):801-5.
10
Biological and biochemical properties of 1-(2-chloroethyl)-3-(beta-D-glucopyranosyl)-1-nitrosourea (NSC D 254157), a nitrosourea with reduced bone marrow toxicity.
Cancer Res. 1977 Mar;37(3):783-7.

引用本文的文献

1
Phase I trials in clinical oncostatic pharmacology.临床肿瘤抑制药理学的I期试验。
Cancer Chemother Pharmacol. 1980;4(1):1-3. doi: 10.1007/BF00255450.
2
Therapeutic evaluation of five nitrosoureas in a human melanoma xenograft system.
Cancer Chemother Pharmacol. 1983;11(3):147-52. doi: 10.1007/BF00254194.
3
Cytostatic action of two nitrosoureas derived from cysteamine.两种源自半胱胺的亚硝基脲的细胞生长抑制作用。
Br J Pharmacol. 1986 Nov;89(3):539-46. doi: 10.1111/j.1476-5381.1986.tb11154.x.

本文引用的文献

1
Therapy of advanced gastrointestinal cancer with the nitrosoureas.亚硝基脲类药物治疗晚期胃肠道癌
Cancer Chemother Rep 3. 1973 May;4(3):27-34.
2
An overview of the status of the nitrosoureas in other tumors.亚硝基脲类药物在其他肿瘤中的应用现状综述。
Cancer Chemother Rep 3. 1973 May;4(3):35-46.
3
3-(Tetraacetyl glucopyranos-2-yl)-1-(2-chloroethyl)-1-nitrosourea, an antitumor agent with modified bone marrow toxicity.3-（四乙酰基吡喃葡萄糖-2-基）-1-（2-氯乙基）-1-亚硝基脲，一种具有改良骨髓毒性的抗肿瘤药物。
4
The multiplication of analogs, the best strategy for rapid extension of the oncostatic arsenal. How can they be compared experimentally?类似物的增殖，这是快速扩充抗癌药物库的最佳策略。如何通过实验对它们进行比较？
Cancer Chemother Pharmacol. 1979;3(4):203-5. doi: 10.1007/BF00254732.
Cancer Res. 1973 Sep;33(9):2005-9.
4
The oncostatic and immunosuppressive action of new nitrosourea derivatives containing sugar radicals.含糖基的新型亚硝基脲衍生物的抑瘤和免疫抑制作用。
Biomedicine. 1975 Dec 20;23(10):410-3.
5
Interspersion of cyclophosphamide and BCG in the treatment of L1210 leukaemia and Lewis tumour.环磷酰胺与卡介苗交替使用治疗L1210白血病和Lewis肿瘤
Eur J Cancer (1965). 1977 Oct;13(10):1095-8. doi: 10.1016/0014-2964(77)90006-8.
6
[Preliminary results of phase I and II clinical trials of RFCNU, a new nitrosourea sugar derivative, in digestive tract tumours].新型亚硝基脲糖衍生物RFCNU用于消化道肿瘤的I期和II期临床试验初步结果
Biomedicine. 1977 Nov;27(8):294-7.
7
Effectiveness of murine leukemia chemotherapy according to the immune state: reconsideration of correlations between chemotherapy, tumour cell killing, and survival time.根据免疫状态评估小鼠白血病化疗的疗效：重新审视化疗、肿瘤细胞杀伤与生存时间之间的相关性
Recent Results Cancer Res. 1977(62):9-12. doi: 10.1007/978-3-642-81174-6_3.
8
Cancer chemotherapy: its role in the treatment strategy of hematologic malignancies and solid tumors.癌症化疗：其在血液系统恶性肿瘤和实体瘤治疗策略中的作用。
Recent Results Cancer Res. 1976(53):1-552.
9
A structure-activity analysis of chemical and biological parameters of chloroethylnitrosoureas in mice.
Cancer Res. 1977 Aug;37(8 Pt 1):2615-8.
10
Chlorozotocin, 2-(3-(2-chloroethyl)-3-nitrosoureido)-D-glucopyranose, an antitumor agent with modified bone marrow toxicity.氯脲佐菌素，2-(3-(2-氯乙基)-3-亚硝基脲基)-D-吡喃葡萄糖，一种具有改良骨髓毒性的抗肿瘤药物。
Cancer Res. 1975 Mar;35(3):761-5.