与软组织肉瘤相关的副肿瘤性肝病

Paraneoplastic hepatopathy associated with soft tissue sarcoma.

作者信息

Sharara A I, Panella T J, Fitz J G

机构信息

Department of Internal Medicine, Duke University Medical Center, Durham, North Carolina.

出版信息

Gastroenterology. 1992 Jul;103(1):330-2. doi: 10.1016/0016-5085(92)91131-m.

DOI:10.1016/0016-5085(92)91131-m

PMID:1612341

Abstract

Paraneoplastic syndromes associated with mesodermal tumors are relatively uncommon. An unusual case manifested by fever, anemia, thrombocytosis, coagulopathy, and idiopathic cholestatic liver dysfunction in association with soft tissue sarcoma is reported. A paraneoplastic syndrome is postulated in the absence of anatomic obstruction of bile flow, evidence of an infectious etiology, or neoplastic hepatic involvement.

摘要

与中胚层肿瘤相关的副肿瘤综合征相对少见。本文报告了一例不寻常的病例，该病例表现为发热、贫血、血小板增多、凝血病以及与软组织肉瘤相关的特发性胆汁淤积性肝功能障碍。在没有胆汁流动的解剖学梗阻、感染病因学证据或肿瘤性肝受累的情况下，推测存在副肿瘤综合征。