Davids P H, Rauws E A, Coene P P, Tytgat G N, Huibregtse K
Department of Hepato-gastroenterology, Academic Medical Center, Amsterdam, The Netherlands.
Gastrointest Endosc. 1992 Jan-Feb;38(1):12-8. doi: 10.1016/s0016-5107(92)70323-x.
This study evaluates the efficacy of endoscopic stenting in 70 patients with noncomplete post-operative biliary strictures. The treatment consisted of placement of two 10 F gauge straight endoprostheses with elective exchange trimonthly, for a 1-year period. Successful endoprosthesis placement was accomplished in 66 of 70 patients (94%). In all 66 patients jaundice subsided. During the stenting period six patients had an operation and six died. In 46 patients the endoprostheses were removed. The mean period of follow-up was 42 months (range, 4 to 99 months). Excellent (asymptomatic, normal, or stable liver enzymes) and good (only one episode of cholangitis) responses were achieved in 83%; restricturing occurred after stent removal in 17%. Prolonged biliary stenting appears to be a safe and effective treatment modality for benign post-operative strictures and a valid alternative to surgery.
本研究评估了内镜支架置入术对70例术后非完全性胆管狭窄患者的疗效。治疗方法为放置两个10F规格的直型内支架，并每三个月进行一次选择性更换，持续1年。70例患者中有66例（94%）成功置入了内支架。所有66例患者的黄疸均消退。在支架置入期间，6例患者接受了手术，6例死亡。46例患者的内支架被取出。平均随访时间为42个月（范围为4至99个月）。83%的患者获得了优秀（无症状、肝功能正常或稳定）和良好（仅发生一次胆管炎）的反应；17%的患者在支架取出后发生了再狭窄。长期胆管支架置入术似乎是治疗良性术后狭窄的一种安全有效的治疗方式，也是手术的一种有效替代方法。
