Rutkowski Ryszard, Rutkowski Krzysztof
Zakład Alergologii Dzieciecej AM w Białymstoku.
Pol Merkur Lekarski. 2005 Jun;18(108):720-3.
Assessment of exhaled nitric oxide (eNO) creates new diagnostic possibilities for evaluation of the inflammatory process especially in children, in whom not all of the contemporary methods of diagnosing respiratory tract diseases are applicable. eNO concentration can be measured in children of all age, including neonates. Direct assessment of eNO is possible with an on-line method, in which NO is directly exhaled into a chemiluminescence analyser. An off-line method is performed by exhalation into a collapsible bag of nonreacting material and analysing the collected air with appropriate analysers. eNO measurement is a non-invasive, repeatable, rapid and sensitive method, producing results even during measurement. Assessment of eNO in children may be used to quantify inflammation in asthma and other respiratory tract diseases specific for this age group. Monitoring of the therapy and response to the anti-inflammatory agents i.e. glucocorticosteroids and anti-leukotriene drugs can also be based on eNO measurement.
呼出一氧化氮（eNO）的评估为炎症过程的评估创造了新的诊断可能性，尤其是在儿童中，目前并非所有诊断呼吸道疾病的方法都适用于儿童。所有年龄段的儿童，包括新生儿，都可以测量eNO浓度。使用在线方法可以直接评估eNO，即NO直接呼入化学发光分析仪。离线方法是通过向不可反应材料的可折叠袋中呼气，并使用适当的分析仪分析收集的空气来进行的。eNO测量是一种非侵入性、可重复、快速且灵敏的方法，甚至在测量过程中就能产生结果。对儿童进行eNO评估可用于量化哮喘及该年龄组特有的其他呼吸道疾病中的炎症。对治疗以及对抗炎药物（即糖皮质激素和抗白三烯药物）的反应进行监测也可以基于eNO测量。
