Thaweboon Sroisiri, Thaweboon Boonyanit, Soo-Ampon Surin, Soo-Ampon Malinee
Department of Microbiology, Faculty of Dentistry, Mahidol University, 6 Yothi Road, Bangkok 10400, Thailand.
Southeast Asian J Trop Med Public Health. 2005 May;36(3):765-8.
Previous studies have shown that Self Arresting Caries Treatment (SACT) may be a useful technique to arrest active caries in Thai preschool children in remote areas. The objective of this study was to examine the effect of SACT on the levels of salivary mutans streptococci and lactobacilli in Thai children. Eighty-two subjects aged 4-6 years from primary school in a remote area of Thailand were recruited for this study. Each subject has at least two pairs of interproximal carious cavities between the first and second deciduous molars, and no history of severe pain. The subjects were divided into the control and SACT groups. The SACT technique was performed by removing food remnants and the surrounding overhang enamel of the carious cavity walls to enlarge the space between the carious cavities. The levels of mutans streptococci and lactobacilli in paraffin-stimulated whole saliva were determined at baseline, 2 and 4 months after treatment compared to those of the control group by the spatula method. The bacterial growth score was divided into three categories: 1 = 0-20 CFU, 2 = 21-100 CFU, and 3 > or = 100 CFU. At baseline, no differences in the mutans streptococci and lactobacilli scores were found between the SACT and control groups (p>0.05). Lower salivary lactobacilli levels were found in the SACT group on follow-up at 2 and 4 months (p<0.05), whereas the mutans streptococci level remained unchanged during these time periods. Our data confirms that the SACT technique can promote a self cleansing condition for interproximal lesions and can reduce the retentive sites in the oral cavity due to a reduction in salivary lactobacilli.
先前的研究表明，自我止龋治疗（SACT）可能是一种在泰国偏远地区学龄前儿童中阻止活动性龋齿的有用技术。本研究的目的是检验SACT对泰国儿童唾液变形链球菌和乳酸菌水平的影响。本研究招募了泰国偏远地区一所小学的82名4至6岁的儿童。每个受试者在第一和第二乳磨牙之间至少有两对邻面龋洞，且无严重疼痛史。受试者被分为对照组和SACT组。SACT技术是通过去除龋洞壁上的食物残渣和周围突出的釉质来扩大龋洞之间的空间。采用刮匙法，与对照组相比，在基线、治疗后2个月和4个月时测定石蜡刺激的全唾液中变形链球菌和乳酸菌的水平。细菌生长评分分为三类：1 = 0 - 20 CFU，2 = 21 - 100 CFU，3 ≥ 100 CFU。在基线时，SACT组和对照组之间的变形链球菌和乳酸菌评分没有差异（p>0.05）。在随访的2个月和4个月时，SACT组的唾液乳酸菌水平较低（p<0.05），而在这些时间段内变形链球菌水平保持不变。我们的数据证实，SACT技术可以促进邻面病变的自我清洁状态，并由于唾液乳酸菌的减少而减少口腔中的滞留部位。
