Peng Dai-Yin, Liu Qing-Yun, Dai Min, Zi Xiao-Mei, Xu Xian-Xiang
Anhui College of Traditional Chinese Medicine, Hefei 230038, China.
Zhongguo Zhong Yao Za Zhi. 2005 Jun;30(12):909-12.
To research the hemostatic effect of total saponins of Yinfenglun.
Bleeding time and volume were deteminded in mice after tails being cut. Clotting times were researched on mice, rats and dogs. Hemostatic mechanism total saponins of Yinfenglun were studied on plasma recalcified time, PT, KPTT and ELT.
TSY at different doses could markedly shorten bleeding time, reduce bleeding volume in mice. TSY also could shorten clotting time of mouse, rat and dog. TSY could influence both intrinsic coagulatian system and extrinsic coagulatian system,and had no effect of antifibrinolysis.
There were obvious hemostatic effect of total saponins of Yinfenglun.
研究阴风轮总皂苷的止血作用。
采用小鼠断尾法测定出血时间和出血量，研究小鼠、大鼠及犬的凝血时间，并观察阴风轮总皂苷对血浆复钙时间、PT、KPTT及ELT的影响，探讨其止血机制。
不同剂量的阴风轮总皂苷能显著缩短小鼠出血时间，减少出血量，也能缩短小鼠、大鼠及犬的凝血时间，对内源性凝血系统和外源性凝血系统均有影响，且无抗纤溶作用。
阴风轮总皂苷有明显的止血作用。
